Pharmacology-Medicine




Online Lecture: Anthelmintic Drugs.

Anthelmintic drugs - drugs acts against infections caused by parasitic worms (helminths).

Anthelmintics are drugs that are used to treat infections with parasitic worms which includes both flat worms, e.g., flukes and tapeworms and round worms, i.e., nematodes. 

Parasitic worms also infect livestock and crops, affecting food production with a resultant economic impact and also of importance is the infection of domestic pets.

Indeed, the companion animal market is a major economic consideration for animal health companies undertaking drug discovery programmes.             

 There is a small repertoire of chemotherapeutic agents available for treatment and in some respects and this situation has been exacerbated by the remarkable success of ivermectin over the last twenty years which has decreased motivation for anthelmintic drug discovery programmes.

This prompts concern, as anthelmintic resistance has been widely reported in livestock and it may also only be a matter of time before this phenomenon occurs in parasites of humans.

 Broad spectrum anthelmintics are effective against parasitic flat worms and nematodes and however, the majority of drugs are more limited in their action, e.g., praziquantel, a drug used in the treatment of schistosomiasis has no activity against nematodes

Click below for a Presentation - Anthelmintic Drugs.

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